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|South Dakota-Nebraska State Line
||US Highway 183 enters South Dakota from Nebraska after crossing the state line.
||Community of Wewela, SD. Limited services.
|County Rad 6302/Rahn Lake Rd
||West to Rahn Lake South Dakota State Recreation Area.
||Community of Colome, SD. Limited services.
|US Highway 18/South Dakota State Highway 49
||SD State Highway 49 goes north to the community of Hamill, SD. Limited services. US Highway 18 proceeds east to the communities of Dallas, SD (limited services) and Gregory, SD. - Gregory City Park: ball diamond, picnic tables, gazebo, benches, tennis courts, disc golf, playground equipment, swimming pools, horseshoe pits. NOTE: Overlaps US Highway 183 to the northwest.
||East to McLaughlin Dam South Dakota State Game Production Area.
|South Dakota State Highway 44
||East to the community of Platte, SD. - South Park: picnic shelter, tennis court, benches, playgrounds, pond, swings. - North Park: sand volleyball court, softball field, playground equipment, picnic shelters. - Swimming Pool Park: swimming pool, playground equipment, picnic area. NOTE: West concurrency with US Highway 183.
||Community of Winner, SD. - Winner City Park: gazebo, picnic tables, playground equipment, basketball court, tennis court.
|US Highway 18/South Dakota State Highway 53
||NOTE: US Highway 18 ends its overlap with US Highway 183. West to the community of Carter, NM (limited services). Community of Jordan Junction, SD (limited services). To the north, SD State Highway 53 overlaps US Highway 183.
|South Dakota State Highways 44/ 53
||NOTE: SD State Highways 44/53 separate from US Highway 183 and head west to the community of New Witten, SD. Limited services.
||East to the community of Ideal, SD. Limited services.
|US Interstate 90
||US Highway 183 terminates at a junction with US Interstate Highway 90. US I-90 goes east to the community of Kennebec, SD. Limited services. West to the community of Vivian, SD. Limited services. LD12e