|Ashland, Oregon - Junction of Oregon Route 99
||Community of Ashland, Oregon, Attractions: Southern Oregon University, Lithia Park offers picnic areas and miles of hiking trails. Ashland Community Hospital, The Oregon Shakespeare Festival, a regional repertory theatre in Ashland, Oregon, ScienceWorks a museum educating visitors in science and technology.
||Intersection Interstate Highway #5, at Ashland, Oregon.
|Dead Indian Memorial Road
||Dead Indian Memorial Road, Ashland Municipal Airport, a public airport located east of the city of Ashland, Oregon, in Jackson County, Oregon, Emigrant Creek Road, Bounds Reservoir, Emigrant Lake County Park, Emigrant Lake,
|Emigrant Lake Road
||Emigrant Lake Road, Emigrant Lake, a reservoir located southeast of Ashland, Oregon, at an elevation of 2,241 feet above sea level. Emigrant Lake Dam,
|Emigrant Dam Access Road
||Emigrant Dam Access Road, Emigrant Dam, on Emigrant Lake, located along Oregon Route #66,
||Junction Oregon Route #273/Old Siskiyou Highway,
|Old Greensprings Highway: Recreation Area
||Old Greensprings Highway, Emigrant Lake County Recreational Area, a recreation site located on the southern shores of Emigrant Lake,
|Hyatt Prairie Road
||Little Hyatt Road, Pacific Crest Trail, Hyatt Prairie Road, Little Hyatt Reservoir, Hyatt Reservoir, a reservoir located at an elevation of 5,000 feet, off Oregon Route #66, Howard Prairie Lake County Park, Howard Prairie Lake, a reservoir located 4,526 feet above sea level Howard Prairie Dam, built on Beaver Creek forms the reservoir.
||Access Road, to, Keene Creek Reservoir, located just off the Oregon Highway #66,
|E Hyatt Lake Road
||E Hyatt Lake Road, Chinquapin Mountain Road, Hyatt Reservoir, a reservoir in Jackson County, Oregon, located at an elevation of 5,000 feet. There is also a winter resort nearby.
|Tub Springs State Wayside
||Tub Springs State Wayside, Tub Springs State Park,
|Mill Creek Road
||Mill Creek Drive, BLM 40-4E-12-1, The Cascade-Siskiyou National Monument, a federally protected area at the junction of the Cascade Range and the Siskiyou Mountains in southwestern Oregon,
|Pinehurst State Airport
||Pinehurst State Airport, a public airport located southwest of Pinehurst, in Jackson County, Oregon,
|Moon Prairie Road
||Moon Prairie Road, Jenny Creek Road, Sugar Pine County Group Campground, located on the southern tip of Howard Prairie Lake/Howard Prairie Reservoir, a reservoir located 4500 ft above sea level in Jackson County, Oregon,
|Camp 3 Reservoir Road
||Camp 3 Reservoir Road, Hayden Mountain, located in the Siskiyou Mountains of Klamath County in Oregon. Hayden Mountain Summit, a mountain pass in Oregon traversed by Oregon Route #66.
|Keno Access Road
||Keno Access Road / BLM 39-7E-31, John C Boyle Reservoir, Topsy Recreation Site, a recreation site located east of Oregon Route #66, at the southern edge of John C Boyle Reservoir, near the John C. Boyle Dam,
|New Spencer Bridge
||New Spencer Bridge, a bridge over John C. Boyle Reservoir, carries Oregon Route #66/Green Spring Highway across,
|Topsy Grade Road: Recreation Site
||Topsy Grade Road, Slip Easy Road, Klamath River Recreation Site, located on the eastern shore of John C. Boyle Reservoir,
|Bill Scholtes Sportsman Park
||Bill Scholtes Sportsman Park, located alongside Oregon Route #66,
|Hamacker Mountain Road
||Hamacker Mountain Road / Chase Mountain Road, to Chase Mountain Lookout, where one can view Mount McLoughlin in the distance from.
||Keno Worden Road, Keno, Oregon, a community in Klamath County, Oregon, southwest of Klamath Falls on the Klamath River near Oregon Route #66 at an elevation of 4,108 feet.
|County Highway #603
||County Highway #603/Clover Creek Road,
|County Highway #787
||County Highway #787, Kems Swamp Road,
|County Highway #781: Lake
||County Highway #781/Round Lake Road, Round Lake,
||Junction United States Highway #97, Oregon Route #140, on the western bank of the Klamath River, west of Altamont, Oregon, a community, in Klamath County, Oregon, south of Klamath Falls, Oregon, a city in Klamath County, Oregon. This is where Oregon Route #66 terminates on the east(its eastern terminus).